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Module BD4: Variation, Inheritance and Evolution

Variation

The differences between individual organisms of the same species is called variation.

Variation can be caused by:

  • Genetic factors
  • Environmental factors

Genetic variation can be caused by:

  • Mutations
  • Fertilisation

Some variations caused by genetic variation include: hair colour, eye colour, attached or detached ear lobes and skin colour. Genetic mutation caused the variations seen in the photos below. An excellent introduction to this module is given on the Science Museum Website.

Intelligence, Sporting Ability and our Health are governed by both environmental factors and genetic factors. There is a lot of debate in the scientific community over the relative importance of each of these. Examples are give in the table below.

  Environmental Factors Genetic Factors
Intelligence Education and upbringing (e.g. if both parents play a musical instrument the child may be more likely to) The physical structure of our brain.
Sporting Ability Coaching, Practising the sport and the facilities available (e.g. if you have nowhere to swim you are unlikely to improve your swimming ability). Coordination and body structure.
Health Diet, Exercise, Smoking and Drinking Genes which contribute to some disorders, e.g. heart disease, breast cancer.

Each human cell (except the sex cells) contain 46 chromosomes. Chromosomes contain genes which are the genetic instructions. If a gene becomes damaged by a mutation it is normally harmful and might cause a disease such as cancer. Mutations happen when a gene becomes damaged in some way. Genes are made of a chemical called DNA which carries the genetic code. If there is a change in the genetic code within the DNA this may cause a mutation. Mutations in the DNA can happen spontaneously within the cell (especially during cell division) or may be caused by environmental factors such as:

  • nuclear radiation
  • chemicals
  • ultra-violet rays and X-rays

In the example shown below there is a small change to the genetic information. The mutation may cause a disease.

Most mutations are harmful. However, some mutations may give an advantageous characteristic to the individual. Every cell contains all of the instructions about how all cells work. However, not all of the genes are used in every cell e.g. a nerve cell has a different set of genes working to a ciliated epithelial cell.

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